NSAID Medications in Eye Care

Pharmaceutical Management with Ophthalmic NSAIDs

Nonsteroidal anti-inflammatory drugs (NSAIDs) play a crucial role in ocular care, particularly in managing pain and inflammation associated with various ocular conditions and surgical procedures. These medications are commonly prescribed following cataract surgery, refractive surgery, and other ocular interventions to alleviate postoperative discomfort and reduce inflammation. By inhibiting cyclooxygenase (COX) enzymes, NSAIDs decrease the production of prostaglandins, which are responsible for inflammation and pain.

NSAIDs are also effective in treating inflammatory eye disorders such as episcleritis, scleritis, and anterior uveitis, providing symptomatic relief and preventing further complications. Topical NSAIDs, like ketorolac and diclofenac, are frequently used due to their targeted action and minimal systemic absorption, making them suitable for localized treatment. These medications help control inflammation, reduce pain, and improve patient comfort during the recovery process.

Understanding the appropriate use, dosing, and potential side effects of NSAIDs is essential for optometrists and eye care professionals to ensure safe and effective treatment. NSAIDs can occasionally cause side effects such as corneal toxicity, delayed wound healing, and increased intraocular pressure, so careful monitoring is necessary. By incorporating NSAIDs into a comprehensive treatment plan, eye care providers can effectively manage ocular inflammation and pain, enhancing patient outcomes and promoting faster recovery.

BrandGenericDosingAmountAgesPregnancyMechanism
Acular
Generic
ketorolac 0.5%
Acular LS 0.4%
qid5mL>2 yearsCCOX inhibitor
Bromday
Generic
bromfenac 0.09%qd1.7/2.5/5mL>18 yearsCCOX inhibitor
Bromsite
Generic
bromfenac 0.075%bid5mL>18 yearsCCOX inhibitor
Ilevro
Generic
nepafenac 0.3%qd+1.7mL>10 yearsCCOX inhibitor
Nevanac
Generic
nepafenac 0.1%tid3mL>10 yearsCCOX inhibitor
Prolensa
bromfenac 0.07%qd1.6/3mL>18 yearsCCOX inhibitor
Voltaren
Generic
diclofenac 0.1%qid2.5/5mLNACCOX inhibitor